Growth of rubella virus in human embryonic organ cultures.

Supportive Effects of Human Embryonic Fibroblast Cell Lines on Growth and Proliferation of EBV-Transformed Lymphoblastoid Cells

Human diploid fibroblast cells produce a spectrum of necessary growth factors and extracellular matrix (ECM) components essential for growth and proliferation of a variety of other cell types. In this study, the effect of five human embryonic fibroblast cell lines, isolated from liver, lung, skin and foreskin tissues, was investigated. A coculture system analyse was employed to cloning efficien...

Evaluation of Cell Mediated Immunity following Rubella Vaccination Using Lymphocyte Proliferation

Background and Aims: Rubella is predominantly a childhood disease that is endemic throughout the world and when rubella outbreaks occur, they are accompanied by birth defects following congenital rubella syndrome. Immunity to rubella virus as a teratogenic agent has an important role for prevention of these serious congenital defects. Lymphocyte proliferation assay is a way for investigation of...

Replication Kinetic of Infectious Laryngotracheitis Virus in Embryonic Chicken Neural Stem Cell

Background and Aims: Infectious laryngotracheitis virus (ILTV) infection causes a highly contagious respiratory disease in poultry leads to significant economic losses in the poultry industry. The genomic and antigenic characteristics between virulent and vaccine strains of ILTV are very similar. The ability of embryonated chicken neural stem (CNS) cell for differential diagnosis of ILTV strain...

Sequence and Phylogenetic Analysis of Wild Type Rubella virus isolated in Iran

Background and Aims: Rubella virus is a human pathogen that causes congenital rubella syndrome (CRS) when infection occurs during early pregnancy. Vaccination programs have been remarkably successful in controlling natural rubella infection and CRS. Moreover, ongoing surveillance for all cases of rubella and CRS is a vital component of a prevention program. Although the WHO recommends the use o...

Use of human diploid cell MRC - 5, for production of Measles and Rubella virus vaccines